








💪 Sleep tight, wake bright — Depend on defense that works all night!
Depend Night Defense Adult Diapers for Women offer up to 12 hours of overnight protection with a super absorbent core that locks away 30x its weight in moisture. Featuring OdorBlock technology for discreet freshness and designed for medium waists (31–37"), these disposable underwear provide comfort and confidence for incontinence and postpartum bladder leaks. Available in convenient 60-count packs (4 packs of 15), they are HSA/FSA eligible for added value.















| ASIN | B0BLG84F6Q |
| Best Sellers Rank | #300 in Health & Household ( See Top 100 in Health & Household ) #6 in Incontinence Protective Briefs & Underwear |
| Customer Reviews | 4.5 4.5 out of 5 stars (11,998) |
| Date First Available | February 23, 2023 |
| Item model number | 10036000551645 |
| Manufacturer | Kimberly-Clark Corp. |
| Product Dimensions | 12 x 18.13 x 9.81 inches; 8.75 Pounds |
E**S
Reliable Overnight Protection with a Comfortable Fit
Reliable Overnight Protection with a Comfortable Fit Depend Night Defense Underwear for Women is one of the most dependable (no pun intended) overnight protection options available. I first purchased these for a family member recovering from surgery, and they’ve since become the go-to for comfort, confidence, and dryness through the night. The material is impressively soft—closer to real fabric than the crinkly texture found in many disposable briefs. The blush color and feminine cut make them feel less clinical, and the fit is snug without being tight. They pull on easily, stay in place even when turning in bed, and don’t bunch or sag after several hours. Performance-wise, they hold up remarkably well. The absorbent core locks in moisture fast, and odor control is effective even after a full night’s use. There’s no noticeable leakage, and the waistband keeps everything comfortably secure. They’re also quiet under clothing, making them discreet enough for day use if needed. A tip: for best results, pick the right size based on both waist and hip measurements—fit makes a big difference in comfort and leak protection. Bottom line: soft, secure, and genuinely protective overnight underwear that delivers comfort and dignity. A top choice for dependable nighttime protection or post-surgery recovery.
A**A
Good for Grandma
I purchased the Depend Night Defense Overnight Underwear for my 96-year-old grandmother, and they’ve truly been a game changer for her comfort and health. We use them every night and also on days when she’s not feeling well enough to get around easily. The fit is secure but gentle, with soft material that doesn’t irritate her skin. Most importantly, they keep her clean, dry, and protected through the night, which has greatly reduced the risk of UTIs, something we struggled with before switching to these. The overnight absorbency is excellent. Even after hours of wear, there’s no leaking, no odor, and she still feels fresh in the morning. The blush color is also a nice touch, it feels a bit more dignified than plain white. We’ve tried other brands, but these stand out for their combination of comfort, absorbency, and skin health. For caregivers, knowing your loved one is protected and comfortable brings incredible peace of mind. Highly recommend for anyone caring for an elderly family member or someone recovering from childbirth who needs reliable overnight protection.
W**W
Life Changing
Life changing! the quality is excellent. It is very absorbent and holds a lot. It is SO great for travelling long distances. The Fit is great and takes the worry away.
K**M
Did the job and are comfy!
I usually get the Always brand in the same size (L) but tried these out this time. They're more comfortable than the Always brand bc they aren't tight around my thighs and hips. Because I'm not constantly pulling or adjusting, they're more durable, in my opinion. I'm using them along with my June cup for added protection and they seem pretty absorbent when necessary. I thought the light color would be weird, but all is well so far. I'll definitely keep these in my monthly arsenal! (For reference, I usually wear a size 14-16 in pants)
M**Y
Truly Reliable Overnight Protection That Finally Works
After trying many brands for my mom, Depend Night Defense is the only one that’s consistently leak proof. She can wear them all night without any discomfort or problems, and they fit her perfectly. It’s such a relief to wake up with dry bedding every morning and know she can rest comfortably. The fabric is soft, not bulky, and holds up really well even on long nights. The only small drawback is that it took us a little while to realize the printed floral design goes in the front. Most other brands have markings or prints on the back, so that was confusing at first. Once we figured that out, everything’s been great. Highly recommend these for anyone who needs dependable overnight protection.
M**N
Depenable
What I like about Depends is they go up a little higher to waist. Padding is good also. They don't rip when putting them on my Mother. Cost is .30cents more each then walmarts or Mckesson but Depends quality is better.
V**R
They really work!
These Night Defense Adult Diapers are just as advertised. They are thick, absorbent and comfortable. There is no bulk nor bulge when wearing them. You can sleep easily at night knowing Depend is doing its job.
J**S
Not leak free for periods
My wife wanted to try these and she wore these on her periods at night for two days. They leaked both nights, so she is switching back to the brand she was getting before, Liv Dry, because they never leak.
L**G
It’s a terrible product which only lasts a day if that! The crotch is fine but the panty part shreds after just a few uses of going to the bathroom 🚽! It literally falls apart so don’t waste your money! Don’t buy! So disappointed ☹️! I’m glad it’s not the first Depend product that I have used otherwise I would never buy Depend products at all! Regular Depends are ok!
A**G
Cumplen du objetivo y son cómodos, solo que el precio varía de un mes a otro y se puede encontrar mas barato en tiendas de autoservicio y farmacias.
B**H
I have purchased this product in the store previously...so, I know that we would be happy with it. With the pandemic, I have been ordering everything online that has been possible. Product arrived in a few days.
A**Y
SSo absorbant
J**N
Great fit
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