---
product_id: 329440482
title: "Douxo S3 Pyo Shampoo, Contains 3% Chlorhexidine & 0.5% Ophytrium, Antiseptic & Hydrating, For Bacterial or Yeast Skin Infections, For Dogs and Cats, 6.7 fl. oz. (200mL)"
brand: "douxo"
price: "€ 30.19"
currency: EUR
in_stock: true
reviews_count: 11
category: "Douxo"
url: https://www.desertcart.ie/products/329440482-douxo-s3-pyo-shampoo-contains-3-chlorhexidine-and-0-5
store_origin: IE
region: Ireland
---

# Visible yeast reduction in 7 days 0.5% Ophytrium natural skin barrier support 3% Chlorhexidine antiseptic power Douxo S3 Pyo Shampoo, Contains 3% Chlorhexidine & 0.5% Ophytrium, Antiseptic & Hydrating, For Bacterial or Yeast Skin Infections, For Dogs and Cats, 6.7 fl. oz. (200mL)

**Brand:** douxo
**Price:** € 30.19
**Availability:** ✅ In Stock

## Summary

> 🐾 Elevate your pet’s skin game—because healthy skin is the new cool!

## Quick Answers

- **What is this?** Douxo S3 Pyo Shampoo, Contains 3% Chlorhexidine & 0.5% Ophytrium, Antiseptic & Hydrating, For Bacterial or Yeast Skin Infections, For Dogs and Cats, 6.7 fl. oz. (200mL) by douxo
- **How much does it cost?** € 30.19 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.ie](https://www.desertcart.ie/products/329440482-douxo-s3-pyo-shampoo-contains-3-chlorhexidine-and-0-5)

## Best For

- douxo enthusiasts

## Why This Product

- Trusted douxo brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Dual-Action Formula:** Combines antiseptic chlorhexidine with soothing Ophytrium for balanced skin health
- • **Hydrates & Strengthens:** Supports skin barrier to reduce irritation and maintain supple, shiny coats
- • **Economical & Easy to Use:** Concentrated formula with pump dispenser lasts longer and locks to prevent leaks
- • **Free From Harsh Chemicals:** No soaps, sulfates, parabens, dyes, or nanoparticles—pure care for sensitive pets
- • **Vet-Recommended #1 Topical Brand:** Trusted by U.S. veterinarians for effective skin infection care

## Overview

Douxo S3 Pyo Shampoo is a veterinarian-recommended antiseptic and hydrating shampoo formulated with 3% chlorhexidine and 0.5% Ophytrium. Designed for dogs and cats with bacterial or yeast skin infections, it effectively disinfects, soothes irritation, and supports the skin’s natural barrier. Free from harsh chemicals, this 6.7 fl. oz. shampoo visibly reduces yeast counts within 7 days while moisturizing and leaving coats soft and shiny.

## Description

Soothes, cleans and strengthens the skin barrier. Moisturizes and detangles the fur to leave the coat soft and shiny. DOUXO is the #1 non-prescription topical brand used and recommended by U.S. veterinarians for treatment of dogs and cats with inflammatory dermatological diseases.

Review: Amazing Stuff - fixed my dog's skin issues! - My dog had maybe a yeast infection, skin allergies... idk. He had scabs and dandruff all over his back and belly, and lots of discoloration on his belly which came out of nowhere, He was constantly itching and I felt so bad for him ): I decided to look into it and found people with similar issues. So, with recommendations, I found this shampoo, and also switched his dog food to a better one. With the switch of his dog food, I can't say that one or the other fixed his skin, or both was the solution, but either way, his skin and coat has made a DRASTIC change in just one month. I have been washing him every 3-4 days with this shampoo for a month now, scrubbing him very well and leaving it to sit on him for 5-10 mins. He hates baths but it's what we have to do! This stuff smells great, it suds up and has a nice lather, rinses well, and leaves his coat feeling soft and clean! I can't complain at all. Yes it is pricey as heck, but if it works how can I complain. when I was researching on the internet for my dog's specific issues, I saw people with similar issues say their dog had a yeast infection, and when they took their dog to the vet, this is what their vet recommended! This is what made me take the jump on the purchase and I was not disappointed.
Review: 5 Stars - HIGHLY Recommend! Works Amazing for Allergies! - Hands down the best dog shampoo I've ever used.y American Pitbull is allergic to everything,I even had him undergo the prick test with the Dermatologist & he's allergic to 40 out of 46 items tested for. So his skin is always broken out, even while doing the Allergy Immunotherapy injections, I'm averaging every 3rd day on giving him another bath & this shampoo is helping him so much! He will be completely broken out, red bumps & hives all over his body, I'll give him a bath & within a few hours, or by the next morning (since I usually bathe right before bed) his skin has significantly improved, half the bumps will be gone, most of the hives are completely gone & the redness is nonexistent! The smell is really great as well, it's a lighter scent, I don't smell any chemicals or any of the normal medicated smell at all & it's light enough you can smell it on your pup if you're up close, but otherwise it's not noticeable. The formula is decently thick, it's not runny at all, but it suds up so great as well - another huge thing most medicated shampoos don't do! You also only need a small amount, it actually advises how much to use on the bottle depending on how large your dog is, but it's so easy to suds up, that you don't need much at all. I have a 64lbs Pitbull & I only use 2 pumps on his whole back, 1 on each side & 1 pump on each leg & that's about it. So the cost is a bit expensive, but it lasts forever with how little you need & with how well it works, its 100% worth it. The pump works great, it has the locking mechanism when you turn the pump to the side, so you don't have to worry about it leaking, we transport it every weekend to our MIL's house, and I just throw it in the bag, never leaked before, you don't have to worry about it. I can't recommend this shampoo enough or stress how well its been working for our 4 dogs!

## Features

- #1 non-prescription topical brand used and recommended by U.S. veterinarians for dogs and cats with infections/inflammatory dermatological disease
- Proven to disinfect, hydrate and help support the skin's ecosystem and reduce yeast counts in 7 days
- Contains ophytrium, a purified natural ingredient that helps support the skin’s physical barrier for supple hydrated skin and helps soothe irritated skin
- Free from soaps, sulfates, parabens, dyes and nanoparticles
- For best results use with the DOUXO PYO Mousse

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B0947674MT |
| ASIN  | B0947674MT |
| Age Range Description | All Life Stages |
| Allergen Information | Hypoallergenic |
| Best Sellers Rank | #434 in Pet Supplies ( See Top 100 in Pet Supplies ) #3 in Dog Shampoos |
| Brand Name | Douxo |
| Color | Translucent |
| Customer Reviews | 4.7 4.7 out of 5 stars (6,909) |
| Date First Available | May 5, 2021 |
| Date First Available  | May 5, 2021 |
| Directions | Use as recommended by your veterinarian. Wet the fur with cool water from the neck down. Using 1 pump for every 4 lbs, gently massage shampoo onto skin abnormalities to reach the skin. Repeat until entire body is lightly coated with shampoo and leave on for 10 minutes. Rinse thoroughly with cool water. Shampoo amount can be doubled for dogs or cats with long and/or thick fur. |
| Included Components | Shampoo |
| Item Package Dimensions L x W x H | 5.94 x 2.48 x 1.81 inches |
| Item Weight | 6.7 Ounces |
| Item model number | D98410M |
| Item model number  | D98410M |
| Liquid Volume | 6.7 Fluid Ounces |
| Manufacturer | Douxo S3 |
| Manufacturer  | Douxo S3 |
| Model Name | PYO |
| Number of Items | 1 |
| Package Dimensions  | 5.94 x 2.48 x 1.81 inches; 6.7 ounces |
| Size | 6.7 oz |
| Special Ingredients | ophytrium |
| Specific Uses for Product | Coat, Skin |
| Target Audience Keyword | Cats, Dogs, dogs |
| Target Species | dog, cat |
| UPC | 850002593426 |

## Product Details

- **Brand:** Douxo
- **Item Form:** Liquid
- **Material Type Free:** Paraben Free,Sulfate Free
- **Product Benefits:** Soothing,Moisturizing,Detangle
- **Recommended Uses For Product:** For Bacterial or Yeast Skin Infections For Dogs and Cats

## Images

![Douxo S3 Pyo Shampoo, Contains 3% Chlorhexidine & 0.5% Ophytrium, Antiseptic & Hydrating, For Bacterial or Yeast Skin Infections, For Dogs and Cats, 6.7 fl. oz. (200mL) - Image 1](https://m.media-amazon.com/images/I/619jLBODSHL.jpg)

## Questions & Answers

**Q: Is there a prescription only version of this shampoo or is this the only one?  My vet prescribed this for my dog and it is less expensive on Amazon**
A: You don't need a prescription! Same thing happened to me.  Go with Amazon

**Q: What do I do if the bottle leaked the shampoo everywhere?**
A: Wipe it up and return for refund.

**Q: Is this antiseptic and antifungal? The bottle in the first picture only says antiseptic**
A: The bottle I bought clearly says antiseptic and antifungal shampoo.  So I would have to say you might have bought wrong one if you wanted both.  Maybe Amazon will allow you to return and rebuy the other one.  Otherwise, this stuff worked well for my dog to give her some relief from all her skin issues.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Amazing Stuff - fixed my dog's skin issues!
*by T***S on November 3, 2025*

My dog had maybe a yeast infection, skin allergies... idk. He had scabs and dandruff all over his back and belly, and lots of discoloration on his belly which came out of nowhere, He was constantly itching and I felt so bad for him ): I decided to look into it and found people with similar issues. So, with recommendations, I found this shampoo, and also switched his dog food to a better one. With the switch of his dog food, I can't say that one or the other fixed his skin, or both was the solution, but either way, his skin and coat has made a DRASTIC change in just one month. I have been washing him every 3-4 days with this shampoo for a month now, scrubbing him very well and leaving it to sit on him for 5-10 mins. He hates baths but it's what we have to do! This stuff smells great, it suds up and has a nice lather, rinses well, and leaves his coat feeling soft and clean! I can't complain at all. Yes it is pricey as heck, but if it works how can I complain. when I was researching on the internet for my dog's specific issues, I saw people with similar issues say their dog had a yeast infection, and when they took their dog to the vet, this is what their vet recommended! This is what made me take the jump on the purchase and I was not disappointed.

### ⭐⭐⭐⭐⭐ 5 Stars - HIGHLY Recommend! Works Amazing for Allergies!
*by H***R on September 15, 2025*

Hands down the best dog shampoo I've ever used.y American Pitbull is allergic to everything,I even had him undergo the prick test with the Dermatologist & he's allergic to 40 out of 46 items tested for. So his skin is always broken out, even while doing the Allergy Immunotherapy injections, I'm averaging every 3rd day on giving him another bath & this shampoo is helping him so much! He will be completely broken out, red bumps & hives all over his body, I'll give him a bath & within a few hours, or by the next morning (since I usually bathe right before bed) his skin has significantly improved, half the bumps will be gone, most of the hives are completely gone & the redness is nonexistent! The smell is really great as well, it's a lighter scent, I don't smell any chemicals or any of the normal medicated smell at all & it's light enough you can smell it on your pup if you're up close, but otherwise it's not noticeable. The formula is decently thick, it's not runny at all, but it suds up so great as well - another huge thing most medicated shampoos don't do! You also only need a small amount, it actually advises how much to use on the bottle depending on how large your dog is, but it's so easy to suds up, that you don't need much at all. I have a 64lbs Pitbull & I only use 2 pumps on his whole back, 1 on each side & 1 pump on each leg & that's about it. So the cost is a bit expensive, but it lasts forever with how little you need & with how well it works, its 100% worth it. The pump works great, it has the locking mechanism when you turn the pump to the side, so you don't have to worry about it leaking, we transport it every weekend to our MIL's house, and I just throw it in the bag, never leaked before, you don't have to worry about it. I can't recommend this shampoo enough or stress how well its been working for our 4 dogs!

### ⭐⭐⭐⭐⭐ Good product that works!
*by L***Y on January 16, 2026*

Finally, relief for our chi’s yeasty skin! Cleared up her itchy red skin immediately and it hasn’t come back. Our girl smells fresh and is comfortable and cozy after her bath again. She seems to stay clean longer too, which means I don’t have to bathe her as frequently.

## Frequently Bought Together

- Douxo S3 Pyo Shampoo, Contains 3% Chlorhexidine & 0.5% Ophytrium, Antiseptic & Hydrating, For Bacterial or Yeast Skin Infections, For Dogs and Cats, 6.7 fl. oz. (200mL)
- Douxo S3 Pyo Mousse, Contains 3% Chlorhexidine & 0.5% Ophytrium, Antiseptic & Hydrating, for Bacterial or Yeast Skin Infections, for Dogs, 5.1 fl. oz. (150mL)
- Douxo S3 Pyo Pads, Contains 3% Chlorhexidine & 0.5% Ophytrium, Antiseptic & Hydrating, For Bacterial or Yeast Skin Infections, For Dogs and Cats, 30 Pads

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*Product available on Desertcart Ireland*
*Store origin: IE*
*Last updated: 2026-02-02*