--- product_id: 293132847 title: "SPM Active® – Specialized Pro-Resolving Mediators* | 30 servings" brand: "metagenics" price: "€ 130.34" currency: EUR in_stock: true reviews_count: 5 category: "Metagenics" url: https://www.desertcart.ie/products/293132847-spm-active-â-specialized-pro-resolving-mediators-30-servings store_origin: IE region: Ireland --- # Standardized SPMs from fish oil 60 softgel servings per bottle Supports immune resolution SPM Active® – Specialized Pro-Resolving Mediators* | 30 servings **Brand:** metagenics **Price:** € 130.34 **Availability:** ✅ In Stock ## Summary > 🛡️ Unlock your immune system’s full potential with Metagenics SPM Active! ## Quick Answers - **What is this?** SPM Active® – Specialized Pro-Resolving Mediators* | 30 servings by metagenics - **How much does it cost?** € 130.34 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.ie](https://www.desertcart.ie/products/293132847-spm-active-â-specialized-pro-resolving-mediators-30-servings) ## Best For - metagenics enthusiasts ## Why This Product - Trusted metagenics brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Pure & Clean Formula:** GMO-free, gluten-free, and unflavored softgels designed for the mindful health enthusiast. - • **Clinically Backed Relief:** Real users report rapid pain and inflammation reduction—feel the difference in days. - • **Daily Wellness Made Simple:** One softgel per serving, 30 servings per bottle—effortless integration into your health routine. - • **Cutting-Edge Immune Resolution:** Harnesses specialized pro-resolving mediators to complete your immune response like never before. - • **Premium Fish Oil Fractionation:** Advanced technology ensures potent, standardized SPM levels for maximum efficacy. ## Overview Metagenics SPM Active® delivers a scientifically advanced blend of specialized pro-resolving mediators derived from fish oil, designed to support the natural resolution phase of immune responses. Packaged as 60 unflavored, gluten-free softgels, this premium supplement offers a clean, potent formula trusted by health-conscious adults seeking effective immune and tissue support. ## Description SPM Active is a revolutionary nutritional product developed through advanced fractionation technology featuring standardized levels of SPMs (specialized pro-resolving mediators) found in fish oil. SPMs play a key role in the resolution (i.e., completion) of an immune response, according to extensive preclinical research. Review: Worth the money - Best brand! They even smell good for a vitamin ! Review: Although Pricey, This Stuff Works! - I had a terrible pinched nerve underneath my shoulder blade. No matter what I did, it would not get better. My naturopath recommended this product. Within a few days, along with some magnesium taurate, I was able to move my arm without pain and the tingling went away. It was amazing and after a week of taking it, I am back to myself. I highly recommend this product, although pricey, it really works!!! ## Features - manufacturer: Metagenics - Item Trademark: METAGENICS - Item Category: Nutritional Supplement ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B019FYPYRA | | Age Range Description | Adult | | Allergen Information | Fish | | Best Sellers Rank | #69,147 in Health ( See Top 100 in Health ) #1,882 in Multiple Vitamin-Mineral Combination Supplements | | Brand | Metagenics | | Brand Name | Metagenics | | Container Type | Bottle | | Customer Reviews | 4.5 out of 5 stars 274 Reviews | | Diet Type | Gluten Free | | Dosage Form | Capsule | | Flavor | Unflavored | | Flavour | Unflavored | | Item Dimensions | 50 x 50 x 89 millimeters | | Item Form | Softgel | | Item Weight | 141 g | | Item dimensions L x W x H | 50 x 50 x 89 millimeters | | Item form | Softgel | | Item weight | 141 g | | Manufacturer | Metagenics | | Manufacturer Part Number | SPMA120 | | Material Features | GMO Free | | Material Type Free | Gluten Free | | Model Name | SPM Active - Specialized Pro Resolving Mediators for Healthy Tissue Function and Immune Support - 60 Count | | Model Number | SPMA120 | | Number of Items | 1 | | Product Benefits | Immune Support | | Special Ingredients | Fish Oil | | Special ingredients | Fish Oil | | UPC | 755571952295 | ## Product Details - **Age range (description):** Adult - **Brand:** Metagenics - **Diet type:** Gluten Free - **Flavour:** Unflavored - **Item dimensions L x W x H:** 50 x 50 x 89 millimeters - **Item form:** Softgel - **Item weight:** 141 g - **Package information:** Bottle - **Product benefits:** Immune Support - **Special ingredients:** Fish Oil ## Images ![SPM Active® – Specialized Pro-Resolving Mediators* | 30 servings - Image 1](https://m.media-amazon.com/images/I/71DmwEPYx2L.jpg) ## Questions & Answers **Q: How much spms are in the product? it says standardized but does not give the amount of spms which will be in mcg.** A: From the Metagenics website: SPM content standardized to 18-hydroxy-eicosapentaenoic acid (18-HEPE) and 17-hydroxy-docosahexaenoic acid (17-HDHA) **Q: Does this help with RA pain** A: I have bad osteoporosis and my neck and it helps immensely to take down that pain! **Q: When will the bariatric advantage version go on sale? this version only has 250mg while the ba version has 500.** A: Hello, if you purchase from Spectrum Supplements you will receive the version with the following ingredients:Supplement FactsServing Size 2 SoftgelsServings Per Container 30Amount Per Serving Calories 5Calories from Fat 5Total Fat 0.5 g Cholesterol <5 mgActive Fractionated Marine Lipid Concentrate† 500 mg SPM content standardized to 18-hydroxy-eicosapentaenoic acid (18-HEPE) and 17-hydroxy-docosahexaenoic acid (17-HDHA)Ingredients: Fractionated marine lipid concentrate (anchovy and sardine oil, and mixed tocopherols (antioxidant), softgel shell (gelatin, glycerin, water, pectin, and sorbitol), and lemon oil. Contains: Fish (anchovy and sardine).This product is non-GMO and gluten free. **Q: How much spm in tablet ?** A: Dear Lizzyamara, Thank you for reaching out to us. We are glad to assist you. Regarding your query, the item has a unit count of 60. If you have any further questions or concerns, please don't hesitate to let us know. Best regards. ## Customer Reviews ### ⭐⭐⭐⭐⭐ Worth the money *by L***D on 2 April 2026* Best brand! They even smell good for a vitamin ! ### ⭐⭐⭐⭐⭐ Although Pricey, This Stuff Works! *by L***Y on 19 May 2023* I had a terrible pinched nerve underneath my shoulder blade. No matter what I did, it would not get better. My naturopath recommended this product. Within a few days, along with some magnesium taurate, I was able to move my arm without pain and the tingling went away. It was amazing and after a week of taking it, I am back to myself. I highly recommend this product, although pricey, it really works!!! ### ⭐⭐⭐⭐⭐ Natural product *by B***R on 11 December 2025* I would highly reccomend this product for joint pain, a natural way to help relieve joint issues. ## Frequently Bought Together - Metagenics SPM Active - Specialized Pro Resolving Mediators for Joint Comfort, Tissue Health & Minor Discomfort Relief* - Non-GMO - Gluten Free - 60 Softgels - Metagenics Vitamin D3 + K - for Immune Support, Bone Health & Heart Health* - Vitamin D with MK-7 (Vitamin K2) - Non-GMO - Gluten-Free - 60 Softgels - 10,000 IU - Metagenics Magnesium Glycinate - Highly Absorbable - Support for Sleep, Stress Relief, Muscle, Bone, Heart & Nerve Health - Gluten-Free - Non-GMO - Vegetarian - 120 Tablets --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.ie/products/293132847-spm-active-â-specialized-pro-resolving-mediators-30-servings](https://www.desertcart.ie/products/293132847-spm-active-â-specialized-pro-resolving-mediators-30-servings) --- *Product available on Desertcart Ireland* *Store origin: IE* *Last updated: 2026-07-06*