Would this work for a 2019 21.5 4K iMac?

No. The tape strips work for a 27" monitor -- the length and placement of the notches won't suit a 21.5"

How difficult is it to remove this adhesive if the machine needs to be re-opened once sealed back up with these strips?

It is not hard to remove at all. One week after i used those strips, the screen fell off of my computer while i was sleeping. I bought a new screen but the logic board got damaged so now i have an 2020 i9 iMac that does not work. I would recommend the the 3M strips instead.

Is there any diagram how to use it? The strips look confusing and fragile. There must be a diagram provided either in this product page or in the box.

If you're talking about where the strips need to be installed I had wondered the same thing until I searched also on Ebay then it showed a diagram. #11 goes in the top left, #12 top right, #13 Right side and so forth all going clock wise in # order.

Anyone know if this will work on Late 2013 14,1 iMacs? 21.5”

14.1?it's fit for Late 2013 iMac 21.5" machine.

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LeFix Replacement LCD Panel Adhesive Tape Strip Sticker + Opening Wheel Tool Kit for iMac 21.5'' 2012 2013 2015 2017(2012-2019) A1418

LeFix Replacement LCD Panel Adhesive Tape Strip Sticker + Opening Wheel Tool Kit for iMac 21.5'' 2012 2013 2015 2017(2012-2019) A1418

Product ID: 270504730

📅Compatible with 2012-2019 iMac 21.5"

📏Precision-fit adhesive strips

🛠️Pro-grade opening wheel tool kit

Description

🖥️ Stick with the best — upgrade your iMac repair game effortlessly!

TRUSTED BY THOUSANDS - 4.6-star rated with nearly 1,800 reviews, this kit is the go-to choice for DIY iMac screen repairs.
ALL IN ONE REPAIR KIT - Includes a professional-grade opening wheel tool kit to make your screen replacement smooth and damage-free.
TAILORED FOR A 1418 MODELS - Specifically designed for iMac 21.5" (2012-2019) guaranteeing flawless compatibility and performance.
ZERO FOLDING ZERO HASSLE - Straight adhesive strips arrive ready-to-use—no bending or folding needed, saving you time and frustration.
SEAMLESS RE SEAL EVERY TIME - Premium adhesive strips engineered for perfect, dust-free application ensuring your iMac display stays firmly in place.

This Replacement LCD Panel Adhesive Tape Strip Sticker kit is designed exclusively for iMac 21.5" A1418 models from 2012 to 2019. It includes six precision-cut adhesive strips and a professional opening wheel tool kit, enabling clean, secure re-sealing of your iMac display after repair or upgrade. Engineered for perfect fit and maximum adhesion, this kit ensures a durable, dust-free installation trusted by thousands of users.

Specifications

ASIN	B07H32CHBJ
Are Batteries Included	No
Best Sellers Rank	#48,525 in Computers ( See Top 100 in Computers ) #46 in Computer Repair Kits
Brand	LeFix
Color	A1418(21.5")
Customer Reviews	4.6 4.6 out of 5 stars (1,799)
Date First Available	2 December 2018
Item Weight	50 g
Item model number	A1418
Manufacturer	LeFix
Package Dimensions	42.01 x 5.21 x 1.3 cm; 50 g

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